Our approach

At InnoGI, we combine decades of experience with cutting-edge in vitro and in silico technology to deliver predictive, physiologically relevant insights into digestion, bioavailability, permeability, ADME, and microbiome interaction. Our TIM systems simulate the gastrointestinal (GI) tract and beyond , helping you make confident decisions in oral drug and nutritional product development.

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30+
Years of experience in mimicking the GI tract
InnoGI combines scientific depth with advanced in vitro and in silico technology to deliver unmatched insights into digestion and absorption
250+
Scientific publications
Our work is backed by a strong foundation of peer-reviewed research, validating the precision and reliability of the TIM® platform
500+
Commercial products tested
From pharmaceuticals to nutritional supplements to food products, our TIM systems have supported the development process of over 500 products, delivering insights that drive strategic decision making

From first call to final report

From your first consultation, you will speak directly with our experts. Together with you, we design a project tailor-made to your product and (research) question(s), employing the most relevant TIM® model, to uncover how your compound behaves in the GI tract. InnoGI will bring, fast that support confident decision-making.

Trust our gut and let’s team-up.

1. Getting started
Introduction to the TIM® platform and our services - Interactive session with mutual introduction - Understand where and how InnoGI can support
Interactive session to understand where InnoGI can support
Discuss approximal timelines and budget
2. Project request & scope
Define the scope and objective of the project
Jointly shape the research approach
Share product (API, ingredient, food) details and existing data
Discuss analytics
3. Contracting
Agreeing terms & conditions
Signing the contract
4. Execution
Pilot phase or experiment(s) (if applicable)
Experiments
Go/no-go (optional)
Sample analysis and data processing
Reporting
5. Completion
Share report, incl. conclusions & recommendations
present results & evaluate

What people say about us

Due to the multistage and biorelevant setup of he TIM-1 model, we were able to evaluate the drug release across the different GI compartments.... During the stage of drug product development, this toll can be extremely usefull to provide guidance in the selection of a lead formulation for the clinical stage. Multiple candidate formulations can be tested in a (relative) short period of time at a fraction of the costs for a clinical study.
we believe that the TIM-1 can be used as a substitute for dog studies with the purpose of assessing clinically significant differences between compound modifications and formulations during product development

Frequently asked questions

What kind of studies can be performed with the TIM® systems?

TIM® systems support a wide range of studies including bioaccessibility, luminal stability absorption, digestion kinetics, and formulation testing for pharmaceuticals, nutraceuticals, and food products.

What is the difference between TIM Upper GI, TIM Colon, TIM Cell and TIM PK?

Each part of the TIM® Platform models  different parts of the human gastrointestinal tract.  TIM Upper GI focus on stomach and small intestine, TIM Colon mimics the colon, TIM Cell mimics the epithial gut wall and TIM PK integrates pharmacokinetics modeling, simulating absorption, distribution, metabolism and excretion (ADME) of a product in the body.

 

What TIM® service or system do I need for my project?

Our experts will guide you. During an consultation call, we’ll discuss your research goals and advise you on the most suitable TIM®  service or system for your project.

Which BCS Class can you test with the TIM® Platform?

We are able to test all BCS Class compounds.

Can I use the the TIM® Platform to test non-oral delivery methods (E.g. intravenous or topical)?

No, our TIM® Services are specifically designed to model the gastrointestinal tract and are intented for testing orally administrered products only.

Can the systems be customized for specific conditions (e.g. pediatric, fasted/fed state)?

Yes, we offer tailored simulations including age-specific, health state, animal species and fed/fasted conditions using actual solid food, such as FDA recommended high-fat meal.

Can I use my own compound, formulation, Food or product?

Absolutely, we work with client provided materials and can advise on preparation and compatibility.

Can I test multiple formulations in one study or project?

Yes, depending on the study setup and objectives, multiple formulations can be compared.

You can use TIM® for dog and pig studies, would it be possible to use TIM® for other species such as mice, rats and monkeys?

In TIM Colon we have a bit of experience with other species (rat, chicken, ducks). Because our systems are computer controlled, we can adjust the settings to simulate any conditions needed. One important criterium is that these conditions need to been described in the literature. If this is requested we will internally discuss the possibilities and proposal. interested in doing a study on a different species? reach out to one of our experts and we are happy to discuss options.

 

 

Can I visit the lab or observe the study?

We welcome collaborations and visits. Please contact us to arrange a suitable date and time.

Can I use images or videos from the TIM® systems in my publication or presentation?

We are happy to be featured in your publications and presentations. If needed, we can provide high-resolution images and video materials. If you plan to use visuals or content related to InnoGI, please reach out to our marketing department to discuss the context. They can advise on correct terminology, crediting, and ensure alignment with our branding guidelines.

Get in contact

We are excited to hear what’s on your plate and how we can help you understand what happens to your product during digestion!

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